Advanced search ?

Object

Title: The influence of a diet on change of genes’ expression for elongases and desaturases of fatty acids in rats

Author:

Drąg, Jagoda

Date:

2011

Type:

Praca doktorska

Abstract:

The structure of fatty acids is a subject to modification in the process of elongation and desaturation, catalyzed by fatty acid elongases and desaturases, respectively. Regulation of gene expression of desaturases and elongases takes place on the stage of gene transcription and is regulated by hormones and different nutrients. Elongases and desaturases are transmembrane enzymes found primarily in the endoplasmic reticulum. The aim of this study was to investigate the dynamic of changes in gene expression of mRNA for elongases 2, 5 and 6 and 5, 6 and 9 desaturases and determine changes in fatty acid composition of total lipids in response to different types of diets, in liver and adipose tissue, as well as changes in lipid profile and glucose concentration in blood serum. Transcripts for elongases and desaturases was investigated using RT-PCR method. In order to determine the fatty acid composition of total lipids gas chromatography was performed. In response to different diet, in liver and adipose tissue results showed differences in expression levels of mRNA for desaturases and elongases and in fatty acid composition. In the liver of animals fed the same diet, varied levels of expression of mRNA for elongases and desaturases as well as a different fatty acid composition were observed in comparison with adipose tissue. In rats’ serum, a lipid profile and glucose level were different depending on the type of diet.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

biochemia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. WydziałFarmaceutyczny z Oddziałem Analityki Medycznej. Zakład Analityki Biochemicznej.

Promoter:

Jerzy Jaśkiewicz

Date issued:

2011

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:3392

Call number:

ZB-115549

ControlNumberVIRTUA:

click here to follow the link

Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Subject and keywords:

elongases desaturases fatty acids diet

Object collections:

Last modified:

Dec 11, 2019

In our library since:

Mar 4, 2013

Number of object content hits:

2 396

Number of object content views in PDF format

2403

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/3392

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-115549 Dec 11, 2019

Objects

Similar

The influence of a diet on change of genes’ expression for elongases and desaturases of fatty acids in rats

Drąg, Jagoda

2011
Praca doktorska

The nutrition model for the elderly during a stay in hospital

Gabrowska, Elżbieta

2005
Praca doktorska

The assesment of the relationship between diet and the estradiol and progesterone levels in menstrual cycles of women between 24-37 years of age.

Merklinger-Gruchała, Anna

2010
Praca doktorska

The influence of metabolic stress factors and quercetin on mitochondrial function ofpreadipocytes

Śliwa, Agnieszka

2013
Praca doktorska

Impact of dietary habits on oral cavity health and dental treatment needs of university students

Kantorowicz, Małgorzata

2016
Praca doktorska

Evaluation of fatty acids profile in patients after heart or renal transplantation

Wilusz, Małgorzata

2018
Praca doktorska

The influence of the selected fatty acids on expression gene of aromatase in progenital cells of human adipose tissue

Dudek, Wojciech

2008
Praca doktorska

The aim of the study was to assess the influence of a single bout of maximal exercise in water at 4°C on blood rheological properties and the composition of fatty acids in erythrocyte membranes of laboratory rats

Teległów, Aneta

2010
Praca doktorska
More
×

Citation

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

This page uses 'cookies'. More information