Title: Assesment of clinical value of imagine and functinal techniques in diagnostic of partial epilepsy in childhood


Precise diagnosis of epilepsy in childhood and identification of it's cause was possible thanks to the progress in new brain imagine techniques and assessment of bioelectrical function of the brain. The aim of study is to assess clinical value of neuroimagine techniques (structural MRI, MRA and HMRS) and functional techniques (EEG,VEEG) in partia} epilepsy diagnostics in children. The study group consisted of 140 children, the age ranged from 2 months to 17 years with partia} epilepsy, hospitalized in Department of Pediatrie Neurology, Collegium Medicum Jagiellonian University, Kraków. The average age was 8 years and 4 months. The average course of disease was 2 years and 4 months. 99 children bad partial epilepsy and abnormalities in MRI. Among them 18.6% bad changes in hippocampus, 17% asymmetry of lateral ventricles, 15% corticosubcortical atrophy. 22% of the study group had abnormal findings on neurological examination, 99.7% of these patients bad abnormalities in MRI. The vast majority of the patients had focal changes in EEG (111/140) with a significant prevalence of unilateral changes (48/111). HMRS was performed in 16/140 children, and in 15 cases results were positive. Conclusions: Abnormalities in neurological examination in children strongly correlated with MRI findings. The correlation with HMRS findings was without statistical significance, there was no correl ; ation with EEG. The structural changes in MRI were found in younger children, whose course of epilepsy was longer than children without MRI changes. HMRS was important in symptomatic diagnosis of partial epilepsy in children without changes in MRI and localized changes in EEG. HMRS results in terms of localization of the changes were rather in agreement with EEG than with MRI findings. Children with partial epilepsy showed localized changes in EEG with prevalence of lateral changes. Changes in hippocampus were the most common in children with abnormalities in MRI. These children showed localized changes in EEG as well. The febrile seizures in children with hippocampus abnormalities were not a risk factor of partia! epilepsy. Migration disorders had big variety of clinical symptoms. This emphasizes the need of MRI in all children with partia! epilepsy.

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Level of degree:

2 - studia doktoranckie

Degree discipline:

neurologia ; pediatria

Degree grantor:

Wydział Lekarski


Kaciński, Marek

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Feb 12, 2024

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Nov 21, 2012

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Edition name Date
ZB-102855 Feb 12, 2024


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