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Title: Risk factors of hearing impairment in preterm infants


Objective: The incidence of sensorineural hearing impairment among premature infants - survivors of intensive care - is high. The purpose of this study was to identify the risk factors of hearing impairment in this group of children. Methods: Prospective cohort study (2.10.96 - 17.11.02). A total of 218 premature infants with birth weight 520-3000g (Me-1300g) and gestational age 22-36 weeks (Me-30) were tested by ABR and divided into 2 groups: with hearing impairment n = 18 and control n = 200. The logistic regression analysis was performed to identify the independent risk factors of hearing impairment. Results: Significant risk factors of hearing impairment were: gestation age (OR: 0,7; 95%CI: 0,6-0,97), hyperbilirubinemia qualified to exchange transfusion (OR: 13; 95%CI: 2,9-64), severe general condition and prolonged use of katecholamines > 8 days (OR: 18; 95%CI: 3,6-96), treatment with amikacin >15 days (OR: 8; 95%CI: 1,6-43), hypoglycaemia ≤ 2,46mmol/l (OR:6; 95%CI: 1,2-23). Mechanical ventilation > 14 days was additional risk factor associated with gestational age (OR: 8; 95%CI: 1,1-65). The model evaluated by logistic regression could predict 13 out of 18 hearing impairment cases (72%). Conclusion: The independent risk factors of hearing impairment in premature infants are: low gestational age or associated with it prolonged mechanical ventilation, hyperbilirubinemia, se ; vere general condition, hypoglycaemia and prolonged treatment with amikacin.

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Level of degree:

2 - studia doktoranckie

Degree discipline:

otorynolaryngologia ; pediatria

Degree grantor:

Wydział Lekarski


Pietrzyk, Jacek J.

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tylko w bibliotece

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Last modified:

Feb 6, 2023

In our library since:

Nov 21, 2012

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Edition name Date
ZB-101894 Feb 6, 2023


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