Title:

Iodine deficiency investigations and it's concequences in adult population of Cracov

Author:

Buziak-Bereza, Monika

Subject:

urinary iodine excretion ; goiter ; nodules ; iodine deficiency

Abstract:

The study aimed to define the status of iodine deficiency, goiter prevalence and thyroid gland rnorbidity in adult population of the city of Cracow evaluated between 1998 and 1999. These data were compared to the results obtained in the same group investigated 1O years before. The analysis included 571 females and 320 males. The mean age was 44 and 42 years in female and male. The mean thyroid gland volume was 15.8 ml in females and 18.3 ml in males. Parenchymatous goiter was diagnosed in 9% of females and 23% of males. Nodular goiter was diagnosed in 23.3% of females and 13.8% of mal es. The mea n urinary concentration of iodine was 1005 ug/l. Ioduria above 100 ug/l was noted in 35.4% of women and 55.8% of men. No correlation was noted between the presence of thyroid nodules and urinary iodinc concentration levels. The hyperthyroidism was revcaled only in 2.1 % of females. Elevated ATMA antibody titter was found in 11.8%. No correlation was observed between ATMA and ioduria levels. Whilc comparing rcsults in the years 1989-90 and 1998-99, two divergent tendencies were observed: a decrease in parenchymatous goiter prevalence and a clear increase in the prevalence of nodular goiter. An increase of mean urinary iodine levels was demonstrated in corresponding sex and age groups in 10-year follow-up. Study supported beneficial results of iodine prophylaxis, the advantageous effect ; s being expressed in a decreased prevalence rate of parenchymatous goiter in adult population and an increase in the mean ioduria values. which reached the expected level of approxirnately 100 ug/l. No adverse side effects of iodine prophylaxis were observed. A clear increase was noted in the prevalence of thyroid nodules, as well as a lack of noticeable effect of iodine prophylaxis on the developrnent of thyroid nodules.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

endokrynologia ; epidemiologia

Degree grantor:

Wydział Lekarski

Promoter:

Szybiński, Zbigniew

Date:

2004

Date issued:

2004

Type:

Praca doktorska

Call number:

ZB-101023

Language:

pol

Access rights:

nieograniczony

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