Obiekt

Tytuł: The assessment of the results of metabolic control in children and adolescents with type 1 diabetes mellitus based on the continuous glucose monitoring system

Abstrakt:

This study was aimed to 1) assess glycemic control in a group of 61 children and adolescents with type 1 diabetes mellitus (DMT1) based on the results of conventional self-monitoring of blood glucose (SMBG) and continuous glucose monitoring (CGM), 2) evaluate the usefulness of CGM in making changes in therapy in order to improve its results. At the beginning of the study, CGM revealed hyperglycemias in all patients and hypoglycemias in 93%. SMBG alone was not able to detect all those glycemic excursions. 100% of patients experienced postprandial hyperglycemias and approximately 85% asymptomatic hypoglycemias, including nocturnal episodes. Based on the results of the first CGM modifications in diabetes therapy were introduced in all patients. After the 3-month follow-up HbA1c decreased significantly in the entire studied group (7,7 vs. 7,3%) without an increase in total daily insulin dose. Second CGM performed at that time revealed significantly fewer hyperglycemias of shorter duration. The number of hypoglycemias did not change throughout the study, but their duration increased significantly. However, there was no increased risk for severe hypoglycemia. The author concludes that intensive insulin therapy, particularly pump therapy using rapid acting analogs is a safe and effective regimen for children and adolescents with DMT1. The routine metabolic control in this age group sh ; ould be extended with periodic monitoring of daily glucose profiles using CGM.

Miejsce wydania:

Kraków

Stopień studiów:

2 - studia doktoranckie

Dyscyplina:

pediatria ; endokrynologia

Instytucja nadająca tytuł:

Wydział Lekarski

Promotor:

Starzyk, Jerzy

Data wydania:

2006

Identyfikator:

oai:dl.cm-uj.krakow.pl:1127

Sygnatura:

ZB-105506

Język:

pol

Prawa dostępu:

nieograniczony

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Data ostatniej modyfikacji:

26 cze 2023

Data dodania obiektu:

21 lis 2012

Liczba wyświetleń treści obiektu:

625

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135

Wszystkie dostępne wersje tego obiektu:

http://dl.cm-uj.krakow.pl:8080/publication/1127

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ZB-105506 26 cze 2023
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