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Title: Estimation of the antioxidant activity of the salvia and oral health state in patients suffering from ischemic heart disease


The aim of the study was to evaluate the oral health state in patients with ischemic heart disease (IHD) in the aspect of the occurrence of the focal odontogenic infection. Equiponderant aim of the research was the assessment of the total antioxidant activity of the saliva (determined by the reductive activity of ferrous ion- FRAP – ferric reducing ability of plasma) and the assay of the antioxidant enzymes (superoxide dysmutase SOD, catalaze CAT) concentration in the saliva. 150 patients between 40 and 70 years of age were examined. The studied group consisted of 100 patients with IHD: including 25 with stabile angina pectoris, 46 with acute myocardial infarction and 29 with past myocardial infarction. The control group consisted of 50 clinicaly healthy people.The dental examination and an X-ray examination was carried out. FRAP was assessed with the spectrophotometry method by Benzi, SOD activity with Mistry and Fridovich’es method and CAT with Aebi’es method. The dental examination revealed significantly lower oral hygiene level, worse periodontium condition and dentition status in patients with IHD. The results of the antioxidant state examination revealed decisively lower level of antioxidant efficiency in patients with IHD compared with those from control group. The presence of interdependence between antioxidant efficiency, dental infections and IHD was revealed. Lower level of oral hygiene, worse periodontium and dentition status, more frequent signs of past and present chronic dental infections may be the evidence that inflammatory diseases of oral cavity can play an important role in the pathophysiology of IHD.

Level of degree:

2 - studia doktoranckie

Degree discipline:


Degree grantor:

Wydział Lekarski


Jadwiga Stypułkowska

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tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

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Last modified:

Jun 24, 2019

In our library since:

Nov 21, 2012

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Edition name Date
ZB-105468 Jun 24, 2019


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