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Tytuł: An evaluation of prognostic value of acute phase proteins in course of acute pancreatitis
Abstrakt:
Acute pancreatitis (AP) is an acute inflammatory process which clinical course varies significantly and in 20% of cases leads to severe, life - threatening disease. This group of patients benefits from early, intensive treatment which significantly improves outcome and decrease of mortality but, so as to institute this therapy an early distinction between mild and severe cases is needed. Recent studies on prediction of course of AP are concentrated on the evaluation of biochemical tests as optimal, single prognostic parameters. The aim of the study was to analyze the usefulness of two of acute phase proteins - serum amyloid A, C-reactive protein - as well as procalcytonin as early predictors of severe AP. Routinely perform biochemical tests were also analyzed so as to assess their potential role as supplementary prognostic parameters in AP. The study population consisted of 40 patients with less than 12 hours of acute symptoms admitted to the 1st Department of General and Gastrointestinal Surgery of Jagiellonian University in Cracow. There were 29 with mild (group I) and 11 with severe AP (group II). The study proves that an early predictor of acute pancreatitis is an mcrease m procalcytonin serum concentration. This parameter distinguishes between mild and severe pancreatitis only 12 hours after the first symptoms have appeared. Among routinely determine b ; iochemical tests it was stated that essential ones in prediction of severe AP are total calcium level and lactate dehydrogenase (day O) and glucose concentration (day I). Others routine biochemical tests did not differentiate between mild and severe pancreatitis.
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Data ostatniej modyfikacji:
19 lip 2022
Data dodania obiektu:
21 lis 2012
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http://dl.cm-uj.krakow.pl:8080/publication/1110
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| Nazwa wydania | Data |
|---|---|
| ZB-105391 | 19 lip 2022 |
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