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Title: The value of air trapping sign in HRCT for evaluation of remodelling in asthma patients


Background: The remodelling is a process of irreversible changes in bronchial walls in patients with asthma. HRCT is non-invasive method which allows to estimate thickening of bronchial wall (a sign of remodelling) in bronchi above 2 mm diameter. An air trapping is a non-specific sign in HRCT. It illustrates changes in small bronchi (under HRCT resolution).Objective: To estimate of air trapping (focal and diffuse) in patients with asthma as compared to controls. In asthma group to compare air trapping and bronchial thickness between patients with aspirin-induced asthma (AIA) and asthmatic patients who tolerated aspirin (ATA). Methods: Each group (asthma and controls) consisted of 30 patients. In asthma group there were 10 patients with AIA. Results: The extension and the degree of advance of focal and diffuse air trapping and thickness of bronchial walls was greater in the asthmatic group compared to controls. In asthma group diffuse air trapping correlated with bronchial walls thickness and diffuse and focal air trapping correlated with some PFTs results. Air trapping was not associated with age, gender, duration and severity of asthma (GINA). There were no statistically relevant changes in air trapping and bronchial walls thickness between AIA and ATA. Conclusions: Air trapping is a sensitive and early marker of remodelling, which allows to noninvasive, indirectly estimate ai ; rways in asthma.

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Level of degree:

2 - studia doktoranckie

Degree discipline:

pulmonologia ; radiologia

Degree grantor:

Wydział Lekarski


Sładek, Krzysztof

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tylko w bibliotece

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Last modified:

Jul 19, 2022

In our library since:

Nov 21, 2012

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Edition name Date
ZB-104241 Jul 19, 2022


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