TY - GEN A1 - Nowak-Kózka, Ilona N2 - Introduction. The monography was carried out by publishing a series of scientific publications on selected extracorporeal blood purification therapies used in critically ill patients in the intensive care unit. Aim of the study. The aim of the series of publications was to present clinical and practical aspects of selected extracorporeal blood purification therapies in patients treated in the intensive care unit. Materiał and methods. The study included patients of Anaesthesiology and Intensive Care Unit of2nd Department oflntemal Medicine of Jagiellonian University Medical College in Krakow, who were treated with therapeutic plasma exchange and continuous renal replacement therapy in years 2009-2017. The prospective observational study and the retrospective observational research included methods of descriptive statistical analysis case studies. Results and conclusions. All of enclosed articles present the clinical and practical aspects of continuous renal replacement therapy and therapeutic plasma exchange. The importance of an individual approach to the patient, taking into account the clinical context, was indicated to ensure the quality of care and achieve the intended therapeutic effects. It was also confirmed the importance of acquiring appropriate theoretical knowledge and practical skills by the therapeutic team. Key role in patient care is played by nurses. Furthe N2 - r studies demonstrated the efficacy of therapeutic plasma exchange with holistic care and pecialist treatment in patients with severe toxic epidermal ecrolysis. It was shown that in severe toxic epiderma} necrolysis unresponsive to corticosteroids, treatment with therapeutic plasmapheresis should be considered. The latest publication from the series deals with the role of adequate pharmacotherapy in the recovery process of critically ill patients. lt empąasizes the importance of the interaction between renal replacement therapy and antibiotic therapy. The results of a prospective observational study suggest that there is no need to modify the dose of meropenem in patients with sepsis after continuous venovenous hemodialysis with regional citrate anticoagulation. The concentration ofhigh-dose (2 g every 8 h) meropenem administered in a prolonged infusion was similar before and after the introduction of renal replacement therapy in patients with sepsis who developed acute kidney injury. CY - Kraków L2 - http://dl.cm-uj.krakow.pl:8080/Content/4585 PY - 2020 KW - continuo us renal replacement therapy KW - intensive care unit KW - sepsis KW - therapeutic plasma exchange KW - toxic epiderma! necrolysis ; nefrologia KW - pielęgniarstwo. T1 - Clinical and practical aspects of selected extracorporeal blood purification therapies in patients treated in the intensive care unit UR - http://dl.cm-uj.krakow.pl:8080/dlibra/publication/edition/4585 ER -