@misc{Biernacka-Fijałkowska_Barbara_Contrast-induced_2010, author={Biernacka-Fijałkowska, Barbara}, address={Kraków}, howpublished={online}, year={2010}, school={Wydział Lekarski}, language={pol}, abstract={Contrast-induced nephropathy (CIN) is a serious complication after exposure to iodinated contrast media. Recent studies show that N-acetylcysteine may play a significant role in prevention of CIN. The aim of his study was to evaluate the incidence of contrast-induced nephropathy in patients undergoing angiography and/or angioplasty procedures, to asses the efficacy of intravenous N-acetylcysteine in prevention of this complication and to asses the long term adverse effects of contrast-induced nephropathy. Results: Contrast-induced nephropathy was observed in 18,4% patients undergoing angiography and/or angioplasty procedures. The incidence of CIN was significantly reduced in patients receiving intravenous N-acetylcysteine as compared to patients receiving hydration with normal saline alone. The search for independent risk factors of contrast-induced nephropathy was performed. This revealed the following predictors: diabetes mellitus and impaired renal function (with eGFR < 60 ml/min/1,72m²), heart failure and volume of contrast medium administered. The risk of CIN was reduced in patients administered isoosmolal contrast medium. Probability of survival free of the following adverse events : cardiovascular death, heart infarct, dialysis, rehospitalization due to cardiac or renal causes was reduced in patients with contrast-induced nephropathy. Conclusions: The rate of long-term a}, abstract={dverse events was higher in patients with contrast-induced nephropathy. Administration of intravenous N-acetylcysteine reduces the risk of CIN.}, title={Contrast-induced nephropathy in patients undergoing angiography and angioplasty procedures}, type={Praca doktorska}, keywords={iodinated contrast media, contrast-induced nephropathy, acute kidney injury, N-acetylcysteine}, }