@misc{Stefańska_Agnieszka_Incidence_2009, author={Stefańska, Agnieszka}, address={Kraków}, howpublished={online}, year={2009}, school={Wydział Lekarski}, language={pol}, abstract={An adrenal incidentaloma is defined as a mass lesion found unexpectedly in an adrenal gland by an imaging procedure performed for reasons other than suspected adrenal pathology. The aim of the study was to estimate the incidence of subclinical hormonal activity and malignancy among patients with incidentally discovered adrenal tumors. 413 patients with adrenal incidentaloma were involved into the study. The adrenal incidentaloma were found mainly in women at the age of 50 to 60. The incidence of the malignant tumors depends on the tumor size and increased at the tumor size of 40 mm, with significantly increased frequency at the size of 60 mm. Metastases were confirmed in 2,2% of patients, the most common primary site was kidney. The progression of tumor size after one year of observation was found in 25,8% of patients. The achieved results showed the better sensitivity of the morning cortisol level < 1,8 g/dl in overnight dexamethasone test for diagnosing hipercorticism, found in 9% of patients with adrenal incidentaloma. The measurement of fractionated urine metanephrines had the high sensitivity with low specificity for diagnosing phecochromocytoma. 45,5% of patients with confirmed primary aldosteronism had normal serum potassium levels.}, title={Incidence of subclinical hormonal activity and malignancy in patients with incidentally discovered adrenal tumors}, type={Praca doktorska}, keywords={pheochromocytoma, primary aldosteronism, adrenal incidentaloma, subclinical Cushing’s syndrome, adrenal carcinoma}, }