@misc{Fronczek_Jakub_Prognosis_2022,
 author={Fronczek, Jakub},
 address={Kraków},
 howpublished={online},
 year={2022},
 school={Rada Dyscypliny Nauki medyczne},
 language={pol; eng},
 abstract={Older critically ill adults face an uncertain prognosis and variable outcomes across different healthcare systems. This study aimed to explain the variation in short-term mortality of patients ≥80 years old hospitalised in intensive care units across Europe and identify an optimal approach to prognostication using the Clinical Frailty Scale. Analysis of data from two international cohort studies showed that patient characteristics, not the organisation of healthcare systems, are responsible for observed differences in short-term mortality between European countries. Considering the small variation in outcomes between individual intensive care units identified after adjustment for confounding in multilevel logistic regression models, the signal of volume-outcome relationship should prompt researchers to verify the hypothesis that intensive care units with a larger annual volume of admissions have slightly lower mortality rates. The added prognostic value of the Clinical Frailty Scale was the largest when all original levels of the scale were used to predict mortality. Oversimplified assessment of the degree of frailty leads to a loss of prognostic information.},
 title={Prognosis and outcomes of older adults admitted to intensive care units},
 type={Praca doktorska},
 keywords={critical care, aged, 80 and over, outcome assessment, health care, prognosis, multicentre studies},
}