@misc{Holcman_Katarzyna_Rita_Role_2020,
 author={Holcman, Katarzyna Rita},
 address={Kraków},
 howpublished={online},
 year={2020},
 school={Rada Dyscypliny Nauki medyczne},
 language={pol; eng},
 abstract={Infective endocarditis (IE) is a life-threatening disease. The hybrid technique of single photon emission tomography and computed tomography with technetium99m-hexamethylpropyleneamine oxime–labeled leukocytes (99mTc-HMPAO-SPECT/CT) is an emerging diagnostic tool in patients with IE. Data on the potential application of this technique in IE and cardiac device-related infective endocarditis (CDRIE) assessment was still limited. Aims of this prospective study included assessment of: (1) the diagnostic performance of 99mTc-HMPAO-SPECT/CT compared with transthoracic echocardiography (TTE) in patients with suspected IE; (2) 99mTc-HMPAO-SPECT/CT diagnostic profile and its added value to the modified Duke criteria (mDuke) in CDRIE diagnostic work-up; (3) the prognostic value of 99mTc-HMPAO-WBC scintigraphy in the course of CDRIE. In patients with suspected IE, 99mTc-HMPAO-SPECT/CT yields a significantly higher diagnostic accuracy and specificity compared to TTE. Included into CDRIE diagnostic work-up, 99mTc-HMPAO-SPECT/CT provides high diagnostic accuracy, inclusion of 99mTc-HMPAO-SPECT/CT into mDuke criteria yields significantly higher sensitivity. In course of CDRIE positive 99mTc-HMPAO-SPECT/CT results are associated with increased rates of in-hospital mortality and complications.},
 title={Role of technetium99m-hexamethylpropyleneamine oxime-labeled white blood cell (99mTc-HMPAO-WBC) scintigraphy in the diagnosis of infective endocarditis},
 type={Praca doktorska},
 keywords={infective endocarditis, radiolabeled leukocyte scintigraphy, scintigraphy, 99mTc-HMPAO-SPECT/CT, HMPAO},
}