@misc{Stryjewski_Piotr_Józef_The_2013, author={Stryjewski, Piotr Józef}, address={Kraków}, howpublished={online}, year={2013}, school={Wydział Lekarski}, language={pol}, abstract={Introduction: syncope is a temporary loss of consciousness, which is the result of global brain hypoperfusion, characterized by rapid onset, short duration, and spontaneous complete resolution.Aim of the study:- analysis of NT-proBNP concentrations in patients with cardiogenic syncope compared to patients with neurogenic syncope.- determination of the threshold values of NT-proBNP to differentiate these groups of patients.- assessment of the impact of serious arrhythmias on value of NT-proBNP.Materials and methods: we studied 100 patients with a history of syncope, in whom, according to ESC guidelines, the final diagnosis was neurogenic (group I) or cardiac syncope (group II).Results: group I - 50 patients (31 F, 19 M) with neurogenic syncope (49 patients vasovagal syndrome) and group II - 50 patients (25 F, 25 M) with cardiogenic syncope (47 of arrhythmias).NT-proBNP was significantly higher in group II in comparison to group I (448.7 ± 212.2 vs. 68.2 ± 64.1, P <0.0001); in the group with VT 526 ± 217 to 225 ± 230 pg / ml in patients without this arrhythmia (p <0.0001), with a third-degree AV block 437 ± 205 compared to 259 ± 246 in those without the disorder (p <0.001).NT-proBNP concentration at 210.5 pg / ml may predict cardiogenic cause of syncope with 98% specificity, 94% sensitivity and 94% negative predictive value.Conclusions:- the concentration of the peptide NT-proBNP}, abstract={of 210.5 pg / ml demonstrated high sensitivity, specificity, and negative predictive value in determining the etiology of syncope.- the concentration of peptide NT-proBNP is higher in patients with syncope, in which there are structural disorders, in comparison to patients without these pathologies.}, title={The role of NT-proBNP peptide in the diagnosis and risk assessment in adult patients with syncope}, type={Praca doktorska}, keywords={sudden cardiac death, NT-proBNP, syncope}, }