@misc{Korpanty_Grzegorz_Applications_2005,
 author={Korpanty, Grzegorz},
 address={Kraków},
 howpublished={online},
 year={2005},
 school={Wydział Lekarski},
 language={pol},
 abstract={The study demonstrates the non-invasive and selective delivery of a gene of human vascular endothelial growth factor (VEGF) using non-viral vector (plasmid) to rat myocardium using ultrasound targeted microbubbles destruction techinque (UTMD). Expression of delivered gene was restricted to the UTMD targeted organ. There was a significant increase in arteriolar density in animals, that received control plasmid with luciferase gene. This finding is probably due to non-specific effects of UTMD on microcirculation and expression of genes that promote arteriogenesis. The exact molecular mechanism of this phenomenon together with the impact of UTMD- stimulated arteriogenesis on coronary blood flow remains to be determined.},
 title={Applications of albumin microbubbles in non-invasive, tissue selective transfer of genetic material into myocardium},
 type={Praca doktorska},
 keywords={contrast echocardiography, non-invasive gene transfer},
}