Search for: [Abstract = "wo patients with an extra chromosomal material and chromosomal marker were detected. In these two cases the identification place of chromosomes fragments origin was executed. The results confirmed the possibility of the high resolution Comparative Genomic Hybridization method \(hr \- the CGH\) in utilization diagnostics of cytogenetics basis of mental retardation and developmental delays. It was also showed the usefulness of the hr – CGH method in diagnostics such changes as\: presence of mosaicism, presence of chromosomal aberrations in the telomers regions and also additional fragments of chromosomes or chromosomal markers identification. Owing that the investigative hypothesis had been rejected. In support of cytomolecular and moleculaa results it can be suppose that received diagnostic algorithm leaning on sQF \- PCR method can be the alternative to the cytomolecular FISH procedure, especially in case when isolated DNA in the only available research material."]
