Search for: [Abstract = "were measured in both groups by ELISA method and expressed in ng\/ml. Results Analysis of risk factors of CAD showed no significant correlations in both groups of patients except of cholesterol level in group I. Significant correlations between RANTES level and endothelial dysfunction measurements \(FMD \(r=0.018, p<0.05\) and vWF \(r=0.007, p<0.01\)\) have been found. Results showed inverse correlation between RANTES level and in IMT assesment \(r=0.012, p<0.05\). MDA as marker of the oxydative stress and RANTES level showed also inverse correlation \(r=0.033, p<0.05\). Inverse correlation have been found between RANTES level and IL\-18 \(p<0.05\). In group II significant correlations have been found between chemokine RANTES level and number of diseased coronary arteries \(p<0.03\). Conclusions Chemokine RANTES level measured in serum is a significant early marker of endothelial dysfunction. Inverse correlations between chemokine RANTES level, IMT and MDA measurements may indicate late distribution of RANTES from peripheral blood to endothelial cells in patients with later stages of atherosclerosis. Elevated RANTES level may evaluate patients to high risk group with endothelial dysfunction. Chemokine RANTES level is a significant marker of severity of coronary disease. RANTES is an early marker of inflammation, but it’s level is lower in patients with diffuse atherosclerosis."]

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