Search for: [Abstract = "usion was necessary after therapy the in 12 patients \(40%\) due to haemorrhagic diathesis signs and symptoms. Normal values of PLT count after the treatment were seen in 3 patients. Leucopaenia was developing during the first week after RIT. The nadir values of 1680\/mm3 were observed in 8 week after the therapy and increased to 3890\/mm3 during subsequent weeks. Fourth grade toxicity was noticed in 8 persons \(26,6%\) and lasted up to 3 weeks. 11 patients \(36,6%\) developed 3 grade toxicity, which persisted in 3 patient for 5 weeks and in 1 person for 10 weeks.Nadir values of neutrophil count \(ANC\) were observed during 6 week after the therapy, mean values of ANC at that time reached 1010\/mm3. After 4 weeks mean ANC values increased to 1810\/mm3. Fourth grade toxicity according to WHO was noticed in 12 patients \(40%\), 3 grade toxicity in 4 persons \(13,3%\). The median duration time of the 4 grade toxicity was 2\-3 weeks. In 6 patients \(20%\) Neupogen was administered due to leucopaenia and granulocytopaenia, 8 persons were treated with antibiotics due to the upper respiratory tract infection. Three patients were admitted to the hospital because of the severe infections \(pneumonia, neutropaenia accompanied by fever\), which however were not life\-threatening. Decrease in mean haemoglobin levels was noticed from the 1 weeks after the therapy reaching nadir values in 8 week after initiatio"]

Number of results: 1