Search for: [Abstract = "stress test in AS patients.The study included 33 adult patients with asymptomatic moderate\-to\-severe AS and 33 controls. The exclusion criteria were\: history of angina, dizziness or syncope, heart failure, left ventricular \(LV\) ejection fraction \(EF\) <50%, history of myocardial infarction, stroke or venous thromboembolism, history or current atrial fibrillation, hyper\- or hypothyroidism, diabetes treated with insulin, oral anticoagulant therapy, severe comorbidities and acute infection. Blood glucose, creatinine, lipid profile, aminotransferases, thyroid\-stimulating hormone, high\-sensitivity C\-reactive protein and routine coagulation parameters \(activated partial thromboplastin time, prothrombin time\-international normalized ratio, fibrinogen\) were determined on admission in all patients. Transthoracic echocardiography and stress echocardiography were performed in all subjects. We also measured intima\-media thickness and ankle brachial pressure index to assess atherosclerotic vascular disease in other arteries. Markers of thrombin generation \(prothrombin 1\+2 fragments \[F1\+2\], peak thrombin generated \[Cmax\], free tissue factor pathway inhibitor, platelet activation \(soluble CD40 ligand \[sCD40L\]\), fibrinolysis \(PAI\-1, TAFI antigen and activity, plasminogen, α2\-antiplasmin, plasma soluble thrombomodulin \[TM\], tissue plasminogen activator \[tPA\] antigen, D\-dimer, clot lysis time \[CL"]

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