Search for: [Abstract = "stant\). The susceptibility to fibrinolysis of the clots was assessed by serial measurements of D\-dimers in the buffer percolating through fibrin gels after addition of recombinant tPA. The factor XI11 Val34Leu polymorphism was also determined. This study demonstrates that decreased permeability and hypofibrinolysis of fibrin clots, previously described in patients with coronary artery disease and their relatives, also characterize patients with symptomatic, advanced peripheral artery occlusive disease. For the first time, it has also been shown that exceptionally low permeability of the fibrin clots and hypo fibrinolysis \(compared to healthy controls and patients with PAOD\) occur in patients with Buerger disease. Markedly increased levels of cellular fibronectin in patients with Buerger disease could be useful in the differentiation of this disease from peripheral atherosclerotic occlusive disease."]

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