Search for: [Abstract = "st and similar therapeutic effect. This result was associated by a significant increase in blood flow and cell proliferation in gingival and lingual mucosa, as well as by a significant decrease in mucosal concentration of pro\-inflammatory interleukin\-1β. Sialoadenectomy alone, without induction of ulcers, caused a reduction in cell proliferation and an increase in concentration of pro\-inflammatory interleukin\-1β in oral mucosa. In these sialoadenectomized rats, administration of ghrelin reversed the sialoadenectomy\-induced reduction in cell proliferation and decreased the sialoadenectomy\-induced increase in concentration of pro\-inflammatory intereleukin\-1β in gingival and lingual mucosa. In sialoadenectomized rats with induction of gingival and lingual ulcers, healing rate of these ulcers was reduced. As in rats without induction of ulcers, this effect was associated with a reduction in blood flow and cell proliferation in oral mucosa, as well as with an additional increase in mucosal concentration of pro\-inflammatory interleukin\-1β. In these rats, administration of ghrelin reversed deleterious effect of sialoadenectomy and ghrelin given at the dose of 8 or 16 nmol\/kg\/dose increased the healing rate of oral ulcers above a value observed in control rats with intact salivary glands. Hypophysectomy alone was without effect on morphology, cell proliferation, blood flow and concentr"]

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