Search for: [Abstract = "scriptors calculated using Marvin program developed by ChemAxon. Besides, an analysis of scanning electron microscope images was used to represent the carrier particles surface roughness. For this purpose, ImageJ program with an additional SurfCharJ package was applied. In total, three databases were constructed for the needs of further computational work. The computational work was carried out using the R environment. The first stage of data analysis was a selection of crucial variables and a reduction of the input vector, which was made using the fscaret package. The following work included models construction and testing, including artificial neural networks, Random Forest, fuzzy systems, rule\-based systems, and mathematical equations created with genetic programming methods. Among the developed models, the best predictions were obtained using genetic programming methods. The predictive capabilities of the best performing models were additionally tested on new experimental data obtained from the literature and research center in Singapore. The model for predicting particles deposition in vitro was also applied to optimize carrier particle features using own\-written computer programme. Proposed directions of carrier modifications were verified by the research center in Singapore."]
