Search for: [Abstract = "s with type 1 diabetes. The specific objectives were\: 1. Review of existing knowledge on etiopathogenesis, symptoms and the latest clinical studies on autonomic neuropathy of the cardiovascular system in the course of diabetes, mainly type 1. 2. Estimation of the incidence of autonomic neuropathy of the cardiovascular system, in the context of the model \(multiple injections vs continuous subcutaneous insulin infusion\) of treatment and metabolic control and clinical characteristics of patients of individual T1DM therapy groups. 3. Determination of possible changes in the expression of genes included in the molecular pathways that may be responsible for the initiation of destruction of nerve tissue in the course of type 1 diabetes. 4. To investigate the hypothesis that DNA methylation \(one of the epigenetic mechanisms\) is involved in the regulation of the expression of genes responsible for the destruction\/regeneration of nerve cells and may play a key role in the pathogenesis of diabetic neuropathy, based on the DNA model of peripheral blood cells. METHODOLOGY AND TEST RESULTS 1. Cardiovascular autonomic neuropathy in the course of diabetes \- the review of actual knowledge. Gastoł J, Pawliński Ł, Kieć\-Wilk B. Postepy Biochem. 2019 Dec 30\;65\(4\)\:306\-312. doi\: 10.18388\/pb.2019_287. Review. Polish. \(review paper\) The paper provided a review of the available lit"]

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