Search for: [Abstract = "rent groups have isolated. Lactobacilli that produced and secreted hydrogen peroxide had proapoptotic influence on cancer cell lines and primary colonocytes. Apoptotic fate of the some cells has been observed after incubation with L. fermentum and L. reuteri, but in most cases Lactobacilli that did not secrete hydrogen peroxide did not have significant influence on caspases activation in vitro. Some of the strains can even protect from the apoptotic process initiated by pathogen and proapoptotic substances. Protective effect of these H2O2 non\-producing Lactobacilli can also be seen in case of actin filaments cytoskeleton. Addition of hydrogen peroxide producing Lactobacilli or their supernatant resulted in destruction of actin filaments and the loss of cell shape and contact. The purpose of this work was to better understand the role of Lactobacillus as commensal bacteria and their role in tissue homeostasis. Better understanding the role of Lactobacillus strains can result in improved prophylactic effect of probiotics."]

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