Szukana fraza: [Abstrakt = "reactions, were subjected to an oral challenge test with a non\-opioid analgesic and obtained a negative result. After the assumed period of time, information about possible subsequent exposures to a given drug and its tolerance was collected. After data collection and database creation, all statistical analyzes were performed using Statistica 13 software \(TIBCO Software Inc., USA\). For continuous variables, nonparametric U\-Mann Whitney tests were used, and Pearson's correlation coefficient r was calculated for particular variables. Differences in proportions between groups were compared using the Chi\-square test. For the assessment of paracetamol\-related hepatotoxicity risk, logistic regression models were built and odds ratios were calculated. A p\-value less than 0.05 was considered statistically significant. Summary of results and conclusions In the first study, We identified in EudraVigilance 4,589 reports on serious adverse events related to hypersensitivity symptoms, of which 58 were fatal. Reports containing information on hypersensitivity symptoms accounted for 27.3% of all reports of serious adverse events. In the analyzed reports, symptoms of hypersensitivity were recorded 9,489 times. The most common symptoms reported were 'angioedema', 'exanthema' and 'urticaria'. The most serious symptoms included Stevens\-Johnson syndrome, toxic epidermal necrolysis and anaphyla"]
