Search for: [Abstract = "pharmacokinetic parameters of antibacterial agents under investigation. The most important factor leading to this variability was age \(first of all for CFU\) accompanied by renal insufficiency \(for CPX and CFU\). In addition, the present study revealed that both PK\/PD parameters \(Cmax\/MIC90, AUC0\-24\/MIC90, tc>MIC\) and MIC breakpoints may used as the equivalent methods for the prediction of the antibioticotherapy efficacy. Taking into account PK\/PD criteria, the usually used dosage regimens of the antibacterial drugs studied would require dosage individualization in most patients from both therapeutic and economic standpoints."]

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