Search for: [Abstract = "ot show any difference between the two groups, with and without comorbid ventricular arrhytmias, in relation to the examined polymorphisms of both genes. However within the group of patients with ventricular arrhytmias it has been revealed that the presence of allel G of polymorphism of ATP2A2 gene is strongly correlated with elevated systolic blood pressure and enhanced left ventricle ejection fraction. No direct relationship between any of polymorphisms of the examined genes and the incidence of ventricular arrhytmias in the course of CHD has been proved, but as the hypothesis of ventricular arrhytmias being a special manifestation of CHD reflecting the severity of atherosclerosis is commonly recognized it is advisable to conduct a similar analysis within a larger group of patients and taking other polymorphisms changing the function of SERCA2A proteins \(e.g., phospholamban\), not examined in this study, into account as well. The another reason justifying the need for further investigation is the fact that within the whole group of patients examined the genotype increasing the propensity for the development of atherosclerosis was predominant."]

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