Search for: [Abstract = "of infection\) in 17.6% of residents. The risk of colonization \(presence in the wound or vestibule of the nose\) was significantly related to the type of care \(ZOL vs. DPS\) and the general stats of the resident\: the presence of urinary or catheter incontinence in the urinary bladder, feeding by gavage, and particularly low Barthel score and mobility restrictions. For the S.aureus infection the following factors were also significantly important\: previous colonization of MRSA, and the presence of chronic wounds, especially leg ulcers. Multivariate analysis indicated that the risk of MRSA was remarkably associated with\: age, physical activity and chronic wounds. Residents with MRSA were highly more often hospitalized due to infections, than those with the MSSA phenotype. S.aureus strains isolated from infections were significantly resistant to fluoroquinolones, tobramycin and amikacin.In total, from various forms of infections isolated from neonatal patients and long\-term care residents 49 strains were with the MRSA phenotype. Genetic typing was carried out with the use of a pulse electrophoresis method PFGE. Strains from neonatal infections \(MSSA and MRSA\) and MRSA strains from long\-term care residents \(colonization and\/or infection\) were subjected to this method. Strains isolated from newborns were additionally catalogued by the spa\-typing method and the type of chromosomal SCCmec cassette was identified.PFGE typing showed that the majority of MRSA strains isolated from neonatal infections were characterised by unique pulsotypes. The vast majority of MRSA strains \(14 out of 16\) had an identical pulsotype, they were included in one clone. Strains with identical pulsotypes came from the NICU department of one hospital. In PFGE analysis of MRSA strains derived from LTCF residents \(n=33\) 5 major clonal groups were detected. The most frequent one was pulsotype A, it was demonstrated in 14 strains.The spa gene from 16 MRSA strains was sequenced with the use of spa\-typing. The most common spa type was t015, it occurred in 15 of the tested strains. One strain had the type spa t011. The type of chromosomal cassette SCCmec within which the mecA gene responsible for the MRSA phenotype is coded was also specified in MRSA isolates. The most frequently detected type of chromosomal cassette is SCCmec IV. By comparing the results obtained with different genotyping methods, it was shown that among the tested neonatal MRSA isolates, the isolates with the t015 spa type and the SCCmecIV are the largest group.So far, in Poland there have been realized no multicentre studies concerning MRSA nosocomial infections, the presented data are the first to concern such key populations as neonatology and geriatrics in modern medicine. It was found\:1"]

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