Search for: [Abstract = "of circulating erythrocytes, platelets, leukocytes and neutrophiles were decreased in splenic blood comparing to peripheral blood. Lymphocyte count was similar in splenic and peripheral blood and lymphocyte B count was increased in splenic blood. The number of IgM and class\-switched memory B cells was incresed in splenic blood. The number of class\-switched plasmablasts, naïve, transitional and activated B cells was similar in splenic and peripheral blood.After splenectomy the number of circulating erythrocytes and platelets in peripheral blood was increased, the number of leukocytes was not changed, and the number of neutrophiles was decreased. Also, total lymphocyte and B cell counts were increased after splenectomy.The increase in B cell count was associated with increase of naïve and transitional B cell numbers. The numbers of memory B cells, class\-switched plasmablasts and activated B cells remained unchanged after splenectomy.These results suggest that the spleen continuously releases memory B cells into bloodstream. Splenectomy seems to affect the peripheral development of B cells, although it do not affect the numbers of circulating memory B cells. The clinical significance of these observations in regard to the patophysiology of postsplenectomy infections remains not entirely clear."]

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