Search for: [Abstract = "o substituent at the 8\-position. For hypotensive activity, however, the most advantageous is the presence of the phenoxyethylpiperazine group at the 7\-position of theophylline, and the 2\-benzylamino\- or 2\-pyridylmethylamino substituent at the 8\-position. Hypotensive effect of the studied compounds most probably results from their α\-adrenolytic and spasmolytic activity, whereas the antiarrythmic activity in the model of adrenaline arrythmia results from blocking α\-adrenergic receptors."]

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