Search for: [Abstract = "nterobacter cloacae \(n = 7, found in 16.7% of patients\), Escherichia coli \(n = 7, found in 16.7% of patients\), Proteus spp. \(n = 4, found in 9.5% of patients\), and Serratia marcescens \(n = 2, 4.8% of patients\), and Serratia liquefaciens \(n = 2, 4.8% of patients\). Before modification, PVC had a contact angle of 86±2 degrees. Wettability is one of the key factors affecting bacterial adhesion Based on the conducted experiments, it was found that the optimal parameters for modifying the PVC surface with oxygen plasma are\: 50 W, 0.2 mbar and 180 sec. The lowest contact angle with the selected parameters was 32 ±2 degrees. The one\-stage synthesis of gentamicin nanoparticles and their deposition on the PVC surface were conducted according to known schemes developed by the Surface Chemistry Group of the Jagiellonian University. The presence of the antibiotic on the surface was confirmed using FTIR by locating binding characteristics for gentamicin, and its release profile from the surface was assessed \(OPA method\). The cytotoxicity of gentamicin nanoparticles was evaluated using the lung adenoma cell line A549 cell line. IC\-50 was assessed in 2\-time intervals \(1 and 24 hours\), setting its value at 1.25 mg\/200 μl \(6.25 mg\/1 ml\). The largest decrease in viable cells was observed after exceeding the concentration of 0.31 mg\/200 μl \(1.55 mg\/1 ml\) from 95% to 60% at the conc"]
