Search for: [Abstract = "ncentration in blood was measured by enzymatic method \(ADH\) and acetaldehyde, methanol and acetone concentrations by using headspace gas chromatography. Because of differences of ethanol concentrations, on admission, in two examined groups \(alcoholics and social drinkers\) the normalization of acetaldehyde results were performed by dividing its concentrations by ethanol concentrations for each sample. The same procedure was carried out for methanol and acetone. Significant faster elimination of ethanol in alcoholic individuals was elicited \(β60 = 0.25 for alcoholics and 0.13 for social drinkers\). The results of mean acetaldehyde concentrations were higher in alcoholics then social drinkers, but these differences were not statistical significant \(except results obtained from blood taken on addmision\). There was not significant difference between examined groups in acetaldehyde\/ethanol ratio, in each time. These results suggest, that measurement of acetaldehyde concentration in man acutely poisoned with ethanol, do not allow to distinguish alcoholics from social drinkers. Results of classical markers of alcoholism as AST, ALT, GGT activity and MCV were statistical significant higher in alcoholic individuals."]

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