Search for: [Abstract = "mpared with controls, but the difference was not significant \(p > 0.05\). Conclusions The results of this study confirm the clinical utility of the presented method for stool sampling and CE\-UV for SCFA identification and measurement. The fecal SCFA profile may be used for a noninvasive assessment of IBD activity. Our study showed that patients with active IBD have reduced fecal SCFA levels as well as isovaleric acid levels, while they have increased fecal lactic acid levels. The SCFA profile does not differ between the types of IBD \(UC vs CD\). Serum TNF\-α levels may serve as a marker of IBD activity. However, no such potential was revealed for the other cytokines\: IL\-6, IL\-10, IL\-17, and IL\-22. There was no correlation between serum cytokine levels and the individual SCFAs. Patients with active IBD show a lower mRNA expression for tight junction proteins \(claudin 2 and ZO\-1\) and a higher mRNA expression for iNOS and PPAR\-γ, as compared with IBD patients in remission."]

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