Filters

Search for: [Abstract = "ll patients to examine them for CHD\: resting electrocardiography, treadmill exercise electrocardigraphy, echocardiogram and invasive examination of coronary arteries – coronarography. A number of the laboratory tests of blood plasm that have conducted to assess risk factors of CHD\: glucose level, glucose tolerance test if necessary, lipid profile, electrolytes levels. Additionally BMI has been measured na arterial blood pressure taken. A specimen of full vein blood has been taken to isolate DNA out of leucocytes with the view to investigating polymorphisms. The isolated genetic material has ben amplified using PCR method and then treated with restriction enzymes and the fragments obtained were separated by electrophoresis \(RFLP method\). Using the above procedure the incidence of particular alleles of examined polymorphisms of promotor regions, 108T\/C in PON1gene and \-491C\/G of ATP2A2 in gene, has been investigated. Next statistical analyses were conducted to compare the incidence of particular genotypes in both groups and to assess the relationship between risk factors and alleles and incidence of ventricular arrhytmias. No statistically significant differences between the two examined groups were revealed in terms of incidence of particular alleles in the examined polmorphisms of PON1 and ATP2A2 genes and in terms of genotype distribution. The evidence from the study did n"]

Number of results: 1

items per page

This page uses 'cookies'. More information