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Search for: [Abstract = "incubated with EPA \+ LOVA \+ LPS or EPA \+ LOVA \+ TNF\-α a significant decrease in mRNA levels for VCAM\-1, PTGS1 \(prostaglandin\-endoperoxide synthase 1\), PTGS2, and an increase in gene expression for NOS3 was noted. Repression of VCAM\-1 and ICAM\-1 adhesion molecules and PTGS1 and PTGS2 gene was observed following supplementation of HUVEC cells with EPA \+ LOVA and ARA \+ LOVA. The presented experiments' results indicate the anti\-inflammatory, antioxidant and pro\-resolving properties of eicosapentaenoic acid and an essential role in the modulation of these processes by n\-6 fatty acids and lovastatin. Supplementation with polyunsaturated fatty acids seems to exert a therapeutic effect in inflamed endothelial cells."]

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