Search for: [Abstract = "in the course oi experimental acute pancreatitis. Leptin, a 167 amino\-acid peptide takes a part in the regulation of body weight, food intake, energy expenditure. Leptin receptor has been detected in heart, placenta, lungs, liver, skeletal muscles, kidney, pancreas, spleen, prostate, ovaries, testis, small intestine and colon. Apart from adipose tissue leptin is produced in placenta, skeletal muscles, pituitary gland and primarily in the stomach. Leptin takes a part in the protection of gastric mucosa against acute damage. The presence of leptin receptor on pancreatic beta cells suggests that leptin could affect endocrine pancreatic function. That hormone influences also exocrine pancreatic secretion. Exogenous leptin, administered centrally or parenterally protects pancreatic gland from acute damage induced by subcutaneous infusion of caerulein on the course of acute experimental pancreatitis in the rats. Leptin exerts also the protective action in the ischaemic model of experimental acute pancreatitis. Ghrelin, 28\-amino acid peptide is produced mainly in the gastric tissue, but its presence has been proved in hypothalamus, pituitary gland, ileum, kidney, placenta, heart, T and B lymphocytes, thyroid gland, lungs, ovaries, testis and pancreas. Ghrelin has been regarded as the most powerful orexigenic and fat deposition factor in the mammals. Numerous studies published recen"]

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