Szukana fraza: [Abstrakt = "ield test. In addition, in the forced swimming test, Fomitopsis officinalis selectively increased the occurrence of one of the forms of active stress coping \(swimming\) at the expense of another form \(climbing\), while a passive form of stress–coping \(immobility\) remained unaffected. This effect was present in the absence of any supplementation–induced locomotor activity changes \(measured in the open–field test\), which suggests that the forced swimming test results can be interpreted in terms of modulation of distress response. In addition, both oyster mushroom and lion's mane reduced passive coping to an extent analogous to a second generation antidepressant \(fluoxetine\). With regard to cognitive effects, in vivo studies have shown that lion's mane slightly improves long–term memory in mice, and that weight gain\: 1\) may have a negative effect on this cognitive function in control chow–fed animals\; 2\) causes a decrease in the expression of genes coding mTOR and GSK3B kinases in mouse hippocampus, regardless of supplementation. In the attentional set–shifting test, no effect of experimental manipulations was observed, although half of the rats supplemented with Fomitopsis officinalis failed to complete the task, which requires reinforcement learning. Ex vivo studies of protein levels in rat hippocampus showed\: 1\) a decrease in the phosphorylated form of"]
