Search for: [Abstract = "f fusion transcripts in nested PCR. The mean time from increase of WT1 expression level to hematological relapse was 129 days \(range 6\-298\). WT1 expression level higher than 20 WT1 copies \/104 ABL copies after induction chemotherapy was associated with shorter overall survival \(OS\) and after consolidation course – with shorter OS and disease free survival \(DFS\). Cox regression analysis revealed that WT1 expression level after induction and consolidation chemotherapy were unfavourable prognostic factors influencing OS and DFS in patients with acute leukemia. Conclusion\: WT1 expression is an useful marker for MRD monitoring in acute leukemia patients, especially in the absence of other molecular markers. High WT1 expression level after induction and consolidation chemotherapy is an important unfavourable prognostic factor."]

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