Search for: [Abstract = "erature on etiopathogenesis, diagnostics, symptoms, and the therapeutic possibilities of CAN. In addition to well\-established risk factors such as HbA1c or the duration of diabetes, epigenetic dysregulation of gene expression is also important in the etiopathogenesis of neuropathy, which may be expressed, among others, by a different metDNA profile. The gold diagnostic standard of CAN remains to conduct tests using the so\-called Ewing batteries. This method allows to assess the functioning of both the sympathetic and parasympathetic system. The diagnosis of CAN is made when min. 2 of the battery tests are incorrect. In addition, the advancement of CAN is evidenced by the number of incorrect tests \(staging\). 2. Is treatment of type 1 diabetes mellitus \(insulin therapy, metabolic control\) optimal for preventing cardiovascular autonomic neuropathy\? Pawliński Ł, Gastoł J, Fiema M, Matejko B, Kieć\-Wilk B. Endokrynol Pol. 2019\;70\(4\)\:323\-329. doi\: 10.5603\/EP.a2019.0011. \(original work\) The work was a retrospective assessment of a group of 93 patients treated in the Metabolic Clinic in the period 2011\-2015. The therapeutic model used was intensive insulin therapy using multiple insulin injections \(MDII\) or continuous subcutaneous insulin infusion \(CSII\). Biochemical parameters were assessed on the basis of a sample of fasting venous blood and urine donated in the mo"]

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