Search for: [Abstract = "e collected, one derived from the cancer tissue and one from its elear surgical margin. The RCAS1 average relative amount in cancer samples was statistically significantly higher than in elear surgical margin specimens. It was noticed, however that in single cases the RCAS1 average relative amount was higher in elear surgical margin samples than in cancer samples. Thus, two RCAS1 values were compared, elear surgical margin average relative amount to the cancer average relative amount, obtaining tumor environmental indicator \(TEI\) value. lt was analyzed with respect to the tumor size, Iocal Iymph node metastases presence \(according to the TNM classification\), tumor grading, tumor localization, cancer recurrence and prognosis. • Statistically significantly higher TEI value was observed in cases of the largest tumor size \(T3\). • TEI value was compared with the tumor grading and was found to be higher in the cases of high grade squamous cell carcinoma than in the cases of moderately differentiated cancer cells. • The analysis of TEI value and tumor Iocalization revealed the highest TEI values in cases with tumors affecting both pharynx and larynx, where the tumor range transgressed anatomical barriers. • High TEI value was related to poor prognosis. High TEI value was identified in four cases involving patients who, in spite of histopatologically cancer fre"]
