Search for: [Abstract = "divided into two groups based on the Crohn’s disease activity index \(CDAI\). The active disease cut point was CDAI>150 points and the rest were treated as remission. In all subjects dental examination, including medical interview, and the assessment of DMF \( d\-decayed, m\-missing, f\- filling\) index was performed. Special precautions were undertaken to assess the pathologic changes previously described in CD. The saliva production was measured, and the production of cytokines IL\-1beta, IL\-6, IL\-10 i TNF\-alfa was estimated using the ELISA method. Statistical analysis was implemented based on the normality of the data distribution, and adequate statistical tests were used. In patients with active CD when compared to healthy controls \(HC\), there were statistically higher levels of leucocytes count, CRP, fibrinogen, and lower levels of erythrocytes, haemoglobin \(Hgb\), haematocrit \(HCT\) and albumins. The biochemical biomarkers typical for chronic inflammatory disease \(ie. CRP, fibrinogen, albumin\), the blood count parameters including platelets, statistically differed from patients with CD in remission. No differences were observed between groups in DMF, which means no increase tendency to caries was found in CD. The amount of sensitive changes in oral cavity, according to Malins et. al, was as follows\: in 2 \(5%\) a diffused labial and buccal sweelings was observed, in 1 \(3%\) focal"]

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