Search for: [Abstract = "d results suggest that EPA and DHA have anti\-inflammatory and anti\-inflammatory properties. Caco\-2 human intestinal epithelial cells were cultured in parallel. In Caco\-2 cells supplemented with EPA and activated with LPS, the level of pro\-inflammatory proteins was significantly decreased, suggesting the anti\-inflammatory properties of eicosapentaenoic acid. Supplementation of cells with 10 μmol EPA and 25 μmol EPA despite LPS activation resulted in a significant reduction of COX\-2, cPGES, and AHR levels. After LPS activation, the highest concentration of IL\-6 was recorded compared to the control. The addition of EPA significantly lowered the level of IL\-6 in Caco\-2 cells. The highest level of cyclooxygenase 2, cPGES, and FP receptor was observed in enterocytes incubated with toxin A. Supplementation with docosahexaenoic acid at 10 μmol, and 50 μmol significantly lowered the level of the proteins mentioned above, despite the presence of the inflammatory factor. A lower gene expression of cyclooxygenase isoforms was demonstrated in Caco\-2 cells activated with toxin A and incubated with DHA. A significant increase in the expression of phospholipase A2 was also shown in the DHA \+ TOXA groups, compared to the results obtained for TOXA alone. The above results may indicate the reduction of toxin A\-induced inflammation in enterocytes by docosahexaenoic acid. Experimental results demon"]

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