Search for: [Abstract = "areas of mucosal inflammatory hyperplasia and fissuring \(cobblestoning\). Unsensitive changes were\: in 3 \( 8%\) unhealed oral ulcerations , in 3 \(8%\) aphtous ulcerations, in 4 \( 11%\) gingivitis, in 4 \( 11%\) midline lip fissuring, in 5 \( 13,5%\) angular cheilitis , in 1 \( 3%\) inflammation of the tongue and in 12 \( 32%\) paleness of oral mucosa. The amount of saliva production in CD patients was 0,40 \+ 0,16 ml\/min and did not differ depending on the activity of the disease nor to the HC group \(0,36 \+ 0,14\). The IL\-6 in saliva of the CD patients was higher than in HC \(12,09 \+ 9,33 i 4,41 \+ 4,79 pg\/ml respectively\; p=0,034\) and was also increased in CD patients in exacerbation, when compared to CD in remission \(13,85 \+ 9,26 vs 7,23 \+ 7,16 pg\/ml respectively\; p =0,047\). The IL\-10 in the saliva was lower in CD patients when compared to HC group \( 9,35 \+ 13,81 vs 23,70 \+ 16,50 pg\/ml respectively\; p=0,007\) and did not differ inside CD group, when activity of the disease was taken into account. The TNF\-alfa level in saliva of the CD patients was higher, when compared to HC \(30,56 \+ 21,28 vs 6,80 \+ 1,80 pg\/ml respectively\; p=0,018\). A statistical positive correlation between the BMI, HgB, HCT, CRP, fibrinogen, platelet count and albumins level and pathological changes in the oral cavity of the CD patients was observed. No association between the CDAI and pathological changes in"]

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