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Search for: [Abstract = "antibodies were measured by, an immunoenzymatic method \(ELISA\), high sensitivity CRP levels were measured using the immunonephelometric method and using modified Klauss method the level of fibrinogen were measured. The level of leucocytes were measured using automatic analyzer. The following statistical tests were performed\: parametic tests \(Student’s t\-test\) and non\-parametic teats \- chi\-square, Spearman’s rank correlation. Mann\-Whitney’s. Patients with confirmed coronary artery disease had significantly higher levels of hs\-CRP \(2,07 ± 2,34ng\/ml vs 1,37 ± 1,41ng\/ml, p = 0,003\), fibrinogen \(3,96 ± 0,99g\/l vs 3,1 ± 0,36g\/l, p = 0,0002\), and leukocytes \(6,89 x103 ± 1,38 vs 5,2x103 ± 0,86, p < 0,00001\) as compared with healthy subjects. In examined study men group 30% patients with CAD and 6,4% healthy volunteers presented hsCRP concetrations > 3mg\/l, that cause an elevated coronaro\-artery risk in that group. The statistical significant difference in levels of anti\-hsp60 antibodies and IgG and IgA anti\-Ch.p. antibodies has not been proved between study groups. The positive correlation between the level of fibrinogen and hsCRP in patients with CAD and control group was observed \(r = 0,63, p < 0,001 and r = 0,69, p < 0,001\). The level of anti\-hsp60 antibodies did not corelate with presence of elevated level of inflammatory markers and Ch.p. infection. Influence of Ch.p. infection on elevated inflammatory markers in patients with CAD and in healthy subjects was not proved. There was no difference between the level of anti\-hsp60 antibodies, hsCRP, fibrinogen, leucocytes and IgG i IgA anti\-Ch.p. antibodies in patients with CCS I and CCS II as well in patients with CAD and one\-vessel disease or multi\-vessel disease. Type of used method \(PTCA vs PTCA \+ stent\) did not influent on level of anti\-hsp60 antibodies, inflammatory and infection markers in study group of patients. In patients with stable CAD undergoing percutaneous angioplasty in comperison to healthy subjects is confirmed, persistant inflammatory reaction iniciates the whole body activation inflammatory response with subclinical view demonstreted with higher level of C\-reactive protein, fibrinogen and leukocytes. There is no clearly evidence for cause reason for chronic and persistent infection of Ch.p. in developing of atherosclerosis and describing role of Ch.p. infection in atherosclerotic leasions needs futher clarifications. Futher study needs also describing role oh anti\-hsp60 antibodies in etiology of atherosclerosis that can cause to new way of immuno\-inflammatory response using immunotherapy and measure in future anti\-hsp60 antibodies can help to estimate to develop atherosclerosis. Examined inflammatory markers are useful for estimating immuno\-inflammatory process developing in an artery, may have a prognostic value in chosing group with elevated coronary\-artery risk and may cause have change therapy used so far in estimated group of patients."]

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