Search for: [Abstract = "and IMI treatment \(with increased DAGLα expression\), dorsal striatum after URB597 treatment or cerebellum after IMI or NAC treatment. The chronic administration of all investigated drugs\/compounds increased anandamide levels in the hippocampus and dorsal striatum, as well as an increase of anandamide levels in the frontal cortex after NAC treatment and cerebellum after URB597 treatment was noted. Raised levels of anandamide were associated with increased NAPE\-PLD expression in the frontal cortex, hippocampus and dorsal striatum \(after NAC or ESC treatment\), or reduced FAAH expression in the hippocampus and dorsal striatum \( after URB597 or IMI, ESC, NAC administration, respectively\). The 2\-AG levels were increased in the frontal cortex \(IMI, TIA, NAC\), hippocampus \(ESC\) and dorsal striatum \(all drugs\/compounds\) or decreased in the prefrontal cortex \(ESC, NAC\), frontal cortex \(ESC\), nucleus accumbens \(NAC\) and cerebellum \(IMI, ESC, NAC\). These changes were resulted from altered expression of 2\-AG metabolizing enzymes\- expression of 2\-AG synthesizing enzyme \(DAGLα\) or expression of degrading enzyme \(MAGL\). Antidepressant drugs\/compounds altered density and expression of CB receptors. An increase of CB1 receptors density was seen in the cortical structures after chronic administration of ESC, TIA or URB597 and in the hippocampal areas after IMI, ESC, TIA and NAC administration, w"]

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