Search for: [Abstract = "aluates only 6 studies on newer antidepressants, indicating their potential efficacy. Only 2 studies evaluated the influence of fluoxetine on vasomotor symptoms, and only one of them assessed healthy women. The study was designed for 12 weeks. The fastest decrease of menopausal symptoms severity was observed in the first 4 weeks \(p<0,001\). Within the next few weeks the symptoms were further reduced however the results between 2nd and 3rd measurements were not statistically significant \(p=0,3 to p=0,95\). Therefore it seems plausible that this therapeutic option might be particularly useful in short term therapy. Additionally, studies of long\-term \(52 weeks\) use of fluoxetine prove that after some time anorectic effect of the drug is no longer noticeable and patients begin gaining weight. This may be related to changes in receptors and neurotransmitters in the satiety and hunger centre. Admittedly fluoxetine influences appetite. The relation between 5\-HT and satiety control has been well documented on animal models. Destroyed serotoninergic neurons in the central nervous system or blocked neuronal synthesis of 5\-HT cause increased food consumption. Administration of 5\-HT or its precursor cause diminished size and quantity of eaten meals. Throughout the study patients in both groups lost weight. Patients in treatment group lost significantly more weight and the differences betw"]

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