Search for: [Abstract = "The thrombin – mediated conversion of plasma fibrinogeninto fibrin and the formation of clots relatively resistant to fibrinolysis are the final steps in the blood coagulation. Abalance between clot formation and fibrinolysis largely determines clot stability. A fibrin clot composed of compact fibrin fiber networks, resistant to fibrinolysis, predisposes to arterial and venous thrombotic events. Reduced fibrin clot permeability and impaired fibrinolysis have been reported in patients with myocardial infarction, ischemic stroke, but also in patients with venous thromboembolism. Retinal vein occlusion \(RVO\) is the most common primary retinal vascular disease. Its pathogenesis is not fully understood. Depending on thrombus location, there are two main types of RVO\: branch retinal vein occlusion \(BRVO\) and central retinal vein occlusion \(CRVO\). The data on the association between known thrombophilic factors and RVO are inconsistent. The aim of this study was to evaluate ex vivo structure and properties of plasma fibrin clots in patients who experienced RVO. We enrolled 59 consecutive patients with diagnosed RVO \(26 females, 33 males, aged 54.95 ± 11.04 years\) and 59 control subjects matched forage, sex, body mass index \(BMI\), medications, and cardiovascular risk factors. A mean time from the diagnosis to enrolment was 14.4 ± 9.9 months \(range, 5–36 months\).The diagnosis of RVO was"]

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