Search for: [Abstract = "The resistance of MRSA strains was associated with the lack of sensitivity to aminoglycosides \(81%\), lincosamides and fluoroquinolones \(50.6%\). In 2005, it was decided to focus only on hip replacement surgeries which were associated with the highest risk of infection, 479 hip prosthesis patients and 172 patients after knee prosthesis underwent the analysis. Morbidity was found to be 2.3% and 7.0%, respectively. Among many examined, the only significant factor affecting the risk of infection was the length of the surgery \- and only in relation to total knee arthroplasty, ICD\-9\: 81.54 \(T=2.009, p<0.05\). Reoperations were necessary in half of patients diagnosed with SSI after hip replacement and 33.3% of patients after knee replacement. After applying the SSI risk index, the significantly higher risk of SSI after surgery in the knee area was found compared to the reference data. In the analysed period, microbiological confirmation was obtained in 62% of SSI cases, and the share of S.aureus after hip surgery was 16.7%, while after knee replacement\: 40.0%. No MRSA strain was identified and gentamycin resistant strains accounted for 20%, against ciprofloxacin and fusidic acid\: 10% of strains. All of them were sensitive to vancomycin.Newborns with very low birth weight\: S.aureus was an etiological factor in 6,5% of infections cases \(total\: early\+late\), most often in blood infections \(55.2%\) and pneumonia \(39.7%\). The MRSA phenotype was found in 32.8%, insignificantly more frequent in blood infections. The MRSA phenotype was significantly related to time, i.e. it was related to infections detected on average on the 14th day \(vs. 23 days for MSSA, p = 0.0194\). Multivariate analysis did not show a relationship between the phenotype and the clinical form of the infection or the clinical condition of the newborn. Antibiotic consumption expressed as the duration of therapy \(DOT\) and defined daily doses \(DDD\) associated with the treatment of S. aureus infections was not significantly dependent on the phenotype\: DOT for MSSA\: 11.2 and MRSA 12.3 and DDD respectively\: 30.2 and 26.0. A significant difference in consumption was found only in relation to DOT for β\-lactams\: Z=\-2.8, p= 0.005\; for MRSA, the average is 3.5\; SD 1.37\; median 3,5, max 5\; for MSSA, average 7.8\; SD 4.15\; median 7\; max 21. The tested strains were not characterized by significantly high resistance or virulence"]

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