Search for: [Abstract = "The purpose of the study was to define the frequency of alleles of lipoprotein lipase gene polymorphisms, TaqI polymorphism of dopamine receptor gene and polymorphisms of melanocortin receptors 3 and 4 genes in studied population. The relationship between described polymorphisms and obesity, disturbances of lipid and glucose metabolism was also evaluated. The study population consisted of 176 subjects. Phenotypes related to obesity, conventional blood pressure measurements and biochemical testes were assessed. The polymorphisms were identified using the restriction fragment length polymorphism method. The frequency of alleles was following\: for LPL\-H allele T 69,5%, for LPL\-P allele T 49,1%, for Taql DRD2 allele C 79,5%, for G241A MC3R allele G 95,5%. Analysis revealed higher levels of AUC\-TG and LDL\-cholesterol in homozygotes TT of LPL\-H than in carriers of allele G. Analysis of LPL\-P polymorphism revealed higher body mass and circumference of waist in homozygotes TT of this polymorphism as compared to homozygotes CC. Analysis comparing homozygotes CC and carriers of T allele additionally showed that carriers of allele T LPL\-P were characterized by higher levels of WHR. Analysis of LPL haplotypes revealed that patients with haplotype 4 \(homozygotes TT of LPL\-H and carriers of allele T of LPL\-P\) were characterized by the highest values of WHR. There wer"]

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