Search for: [Abstract = "The lowest mean values of haemoglobin \(11,65 g\/dL\) were found during the 4 month after initiation of the treatment \(mean pre\-therapy level was 12,4 g\/dL\). Increase in haemoglobin level was observed 1 month after nadir values were reached. Normal haemoglobin levels or mild anaemia were present in most of the patients. 2 persons developed severe anaemia \(3rd grade of toxicity\) after 1 month after initiation of the treatment and after 3 cycle respectively. Similarly, after subsequent cycles of the therapy decrease in the PLT count was seen, but the mean values were within normal range. Only in 1 patient single measurement of PLT was assessed as the 3 grade toxicity according to WHO.The lowest values of white blood cell count \(WBC\) were seen after 3 and 4 cycle of the treatment. In the subgroup of NET patients WBC decreased by at least one toxicity grade according to WHO in 20 patients. No 4 grade toxicity was observed. Three patients developed 3 grade toxicity. In 1 patient with WBC\-1360\/µl Neupogen was implemented during the 3 month after implementation of the therapy. The influence of the chemotherapy on the CBC and creatinine level in NET patients was analysed. The preceding chemotherapy resulted in lower basal and post\-therapeutic WBC and PLT count as well as higher creatinine levels compared to the chemotherapy\-naïve patients. Some of the differences were statistically sign"]

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